TB500 (Thymosin ??4)
Presentation: 2 cc vial, 2 mg/vial, protected with hologram. Comes without solvent.
TB-500 is a manmade version of the naturally occurring peptide that is present in virtually all human and animal cells, known as Thymosin Beta 4 (Tß4). Studies of TB-500 (Thymosin Beta 4) show that it encourages:
One of the major factors of TB-500 is its ability to regulate Actin. Actin is a cell building protein, which is an essential part of cell structure and movement. Actin, even though there are thousands of proteins in each cell, is about 10% of the total proteins; therefore, Actin plays a very important role in the genetic design of each cell.
This Peptide is a member of the family of related 16 molecules that offer localization and high conservation of sequence in the majority of the tissues of the body as well as the circulating cells. Not only does TB-500 bind to actin it is known for its properties as an actin-sequestering molecule in eukaryotic cells as well as blocking actin polymerization.
In addition to the above, a major factor of TB-500 when it interacts in a specific way with actin in the cytoskeleton of the cell it encourages cell migration. Along with this, it has been shows that a specific central small amino acid long-actin binding domain has characters of wound healing and blood cell reproduction. These characters are noted with the acceleration of migration of keratinocytes and endothelial cells along with producing more extracellular matrix-degrading enzymes.
Research has proven that TB-500 is a very strong natural wound repair factor that also offers anti-inflammatory properties. TB-500 is unlike other repair factors like growth factors as it encourages keratinocyte and endothelial migration. Along with this, it does not bind or stick to the extracellular matrix and has a low molecular weight. The low molecular weight allows the TB-500 to travel long distances through the tissues.